Detalhe da pesquisa
1.
Dynamic regulation of B cell complement signaling is integral to germinal center responses.
Nat Immunol
; 22(6): 757-768, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031614
2.
Interferon-ß acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation.
Immunity
; 55(3): 459-474.e7, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35148827
3.
Design and testing of a humanized porcine donor for xenotransplantation.
Nature
; 622(7982): 393-401, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37821590
4.
Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation.
J Biol Chem
; 298(6): 101985, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483450
5.
Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum.
PLoS Pathog
; 15(12): e1008232, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31860690
6.
Correction: Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation.
J Biol Chem
; 299(1): 102807, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36563463
7.
Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes.
J Biol Chem
; 292(7): 2690-2702, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062577
8.
Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2.
Proc Natl Acad Sci U S A
; 109(26): 10498-503, 2012 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22691502
9.
Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway.
J Biol Chem
; 288(13): 8922-34, 2013 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23386610
10.
Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 Are essential for lectin pathway activation and reveal structural plasticity of MASP-2.
J Biol Chem
; 287(24): 20290-300, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22511776
11.
High affinity small protein inhibitors of human chymotrypsin C (CTRC) selected by phage display reveal unusual preference for P4' acidic residues.
J Biol Chem
; 286(25): 22535-45, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21515688
12.
Mannan-Binding Lectin Promotes Murine Graft-versus-Host Disease by Amplifying Lipopolysaccharide-Initiated Inflammation.
Transplant Cell Ther
; 28(8): 472.e1-472.e11, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35643350
13.
Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model.
J Mol Biol
; 431(3): 557-575, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30543823